Center for Bio-Image Informatics

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Retina Research

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 The Retinal Research Group studies cellular changes that occur following retinal detachment and reattachment. They are also developing new therapies for the treatment of retinal detachment. In this process, they are generating thousands of high quality images of tissue samples in the form of electron micrographs and laser scanning confocal images.

The Retinal Research Group studies cellular changes that occur following retinal detachment and reattachment. They are also developing new therapies for the treatment of retinal detachment. In this process, they are generating thousands of high quality images of tissue samples in the form of electron micrographs and laser scanning confocal images.

In the past, readers were able to access only about one percent of the image-data used in the publication of articles. Thanks to a collaboration between the Retinal Cell Biology Lab and BioImage Informatics, researchers across the world will be now able to access past publications of the Retinal Research Group complete with their entire datasets (often, hundreds of images) through this website.

 


 

Up-regulation of GFAP in response to retinal injury: Its potential role in glial remodeling and a comparison to vimentin expression.

detection of cell nuclei in retinal imagesThe upregulation of intermediate filament proteins GFAP and Vimentin were looked at following both retinal detachment and reattachment. Researchers raised issues regarding the role of these proteins in Müller cells (the radial glia of the retina), specifically their differential expression as they form glial scars on the opposing retinal surfaces.

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The efficacy of delayed oxygen therapy in the treatment of experimental retinal detachment

 Researchers teamed up with a local opthalmologist to investigate the use of delayed hyperoxia to slow or prevent degenerative and gliotic changes initiated by retinal detachment. read more...

Activation of microglia following retinal detachment

 Researchers investigated the differences in microglial activation across four different species: cat, rabbit, ground squirrel and human. These experiments were published July 13th, 2005 in Molecular Vision. read more...